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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCB1 All Species: 26.97
Human Site: S887 Identified Species: 65.93
UniProt: Q9NQ66 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQ66 NP_056007.1 1216 138567 S887 H S Q P A P G S V K A P A K T
Chimpanzee Pan troglodytes XP_001170216 1271 144286 S942 H S Q P A P G S V K A P A K T
Rhesus Macaque Macaca mulatta XP_001116017 1216 138567 S887 H S Q P A P G S V K A P A K T
Dog Lupus familis XP_542896 1210 138183 S881 H S Q P A P G S V K A P A K T
Cat Felis silvestris
Mouse Mus musculus Q9Z1B3 1216 138307 S887 H S Q P A P G S V K A P A K T
Rat Rattus norvegicus P10687 1216 138326 S887 H S Q P A P G S V K A P A K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513474 1217 138978 S887 H S Q P T P G S V K A P A K S
Chicken Gallus gallus Q2VRL0 637 72514 K365 S S P P P R K K A K V K K M K
Frog Xenopus laevis Q32NH8 758 87399 L486 K E R L S Q E L S D C V I Y C
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25455 1318 146373 V1007 K I L D H K S V K E K R L E M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 99.1 92.5 N.A. 96.5 97.3 N.A. 92.5 21.6 23.1 N.A. N.A. 39.9 N.A. N.A. N.A.
Protein Similarity: 100 95.3 99.5 94.9 N.A. 97.9 98.6 N.A. 95.7 34.4 35.1 N.A. N.A. 57.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 20 0 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 20 13.3 N.A. N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 60 0 0 0 10 0 70 0 70 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % C
% Asp: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 10 0 0 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % G
% His: 70 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 20 0 0 0 0 10 10 10 10 80 10 10 10 70 10 % K
% Leu: 0 0 10 10 0 0 0 10 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 80 10 70 0 0 0 0 0 70 0 0 0 % P
% Gln: 0 0 70 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % R
% Ser: 10 80 0 0 10 0 10 70 10 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 60 % T
% Val: 0 0 0 0 0 0 0 10 70 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _